Take care of stray animals either wild kangaroos or cattle on the roads and tracks, do not drive at dawn or during the night.
Various deadly animals live in the area. Saltwater Crocodiles inhabit most river systems and coastal areas, extreme caution should be used when on or near, beaches, rivers, creeks and waterholes. Deadly jellyfish such as the dreaded Box Jellyfish and Irukandji are found in the surrounding sea including around Broome, especially in the Wet. Do not go out swimming, unless you are absolutely certain that the area is perfectly safe.
Except in the centre of the few towns, your mobile phone will not work anywhere, So do not count on it while going to more remote areas.